Hank Azaria

as Perplexo (voice)

as Self - Actor & Matthew's Friend

as Moe (voice)

as Chief Wiggum (voice)

as Jock

as Moe Szyslak / Captain McCallister / Goofy / Buzz Lightyear (voice)

as Frank Dipascali

as Srul Katz

as Jerry Damiano

as Gargamel

as Gargamel (voice)

as Mighty Sven (voice)

as Carlos / Phil (voice)

as Gargamel

as Gargamel (voice)

as Dr. Stan Knight

as Kahmunrah / The Thinker / Abe Lincoln

as Abraham

as Whit

as Professor Frink / Comic Book Guy / Moe / Chief Wiggum / Lou / Carl / Cletus / Bumblebee Man / Male EPA Worker / Dome Depot Announcer / Kissing Cop / Carnival Barker / Counter Man / Apu / Drederick Tatum / Sea Captain / EPA Passenger / Robot / Dr. Nick / Wise Guy (voice)

as Self

as Eddie Brock / Venom

as Claude

as Young Patches O'Houlihan

as Michael Kelly

as Hector Gorgonzolas

as Prof. Groeteschele

as Chief Wiggum / Prof. John Frink (voice)

as Blue Raja / Jeffrey

as Charles Danner

as Bartok (voice)

as David

as Victor 'Animal' Palotti

as Walter Plane

as Carter

as Steven Lardner

as Bartok (voice)

as Agador

as Alan Marciano

as Bud Kent

as Albert Freedman

as Detective

as Thomas Edison

as Eddie Nicholls

as Chaim

as Jim Brockmire

as Craig Huffstodt

as Jay Nichols

as Moe Szyslak / Chief Wiggum / Apu / Comic Book Guy / Carl (voice)