
Overview
Lorenzo Odone, a Virginia 5-year-old, develops a degenerative nerve disease so rare that nobody is working on a cure, so his parents decide to immerse themselves in research and tackle the problem themselves.
Trailer
Crew
DirectorGeorge Miller
WriterGeorge Miller, Nick Enright
Cast

Nick Nolte
Augusto Odone

Susan Sarandon
Michaela Odone

Peter Ustinov
Professor Nikolais

Ann Hearn
Loretta Muscatine

Maduka Steady
Omuori

Aaron Jackson
Francesco Odone

Laura Linney
Young Teacher

Kathleen Wilhoite
Deirdre Murphy

Gerry Bamman
Doctor Judalon

Margo Martindale
Wendy Gimble

James Rebhorn
Ellard Muscatine
Colin Ward
Jake Gimble

LaTanya Richardson Jackson
Nurse Ruth

Jennifer Dundas
Nurse Nancy Jo
William Cameron
Pellerman

Becky Ann Baker
Pellerman's Secretary

Mary Pat Gleason
The Librarian
David Shiner
Clown

Ann Dowd
Pediatrician

Peter MacKenzie
Immunosuppression Doctor
More like this
Keywords
washington dc, usaparent child relationshipmedicinebased on true storyincurable disease1980scomoros
Details
Budget
$30M
Revenue
$7M
TMDb Votes
565
Added May 14, 2026Updated Jun 4, 2026











